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Accelerating Alzheimer's Disease Research

February 25, 2020

According to the Bright Focus Foundation, there are 50 million people worldwide living with Alzheimer’s Disease or dementia. The global economic impact of dementia is estimated at $1 trillion. In the US, total payments for healthcare and long term care facilities related to Alzheimer’s Disease and dementia are expected to cross the $1.1 trillion mark by 2050.
Alzheimer’s Disease is debilitating, causing patients to lose memory and cognitive functions that interfere with daily life. For Alzheimer’s patients, around-the-clock, long term care is inevitable as the disease progresses. Currently, there is no cure.
Many pharmaceutical companies such as Biogen, AC Immune SA, and NerveGen are working on treatments for Alzheimer’s Disease.



NerveGen encountered a breakthrough while developing a nerve regeneration treatment for spinal cord injuries. Their Phase 2 clinical trial for treating symptoms of Multiple Sclerosis will shortly commence to apply this treatment, which unlocks a damaged nervous system’s natural ability to repair itself. It improves plasticity in damaged nerves.
Alzheimer’s Disease is a neurodegenerative disease caused by cell death over time. If there’s a mechanism that can regenerate damaged cells and enable new connections, then the progression of the disease could be slowed down or reversed. NerveGen is involved in developing treatment for Alzheimer’s Disease by adapting their nerve regeneration treatment for spinal cord injuries.
Alzheimer’s Disease is one of the most researched diseases in both clinical and pharmaceutical research. Using ResoluteAI, you can find 137,821 publications, 10 companies, 365 technology transfer opportunities, and 3,561 clinical trials associated with Alzheimer’s Disease to date.

Insights in Data

In the case of researchers from NerveGen, their scientists might only be interested in treatments of Alzheimer’s Disease that use the nerve regeneration technique. Using ResoluteAI’s advanced search tool, it’s easy to narrow results down to 130 publications that specifically reference nerve regeneration.
In recent years, there’s been an increase in research in this area of Alzheimer’s Disease treatment. Four clinical trials are currently being conducted by different institutions.


Medicine and Research, Unsiloed

Nerve regeneration is used in many areas to treat pain, nerve injuries, and even in surgery. Using ResoluteAI’s Explore function, it’s easy to understand the full landscape of medical treatments using only the search criteria “nerve regeneration.” Thirty-four clinical trials are currently underway using this treatment.
Learning how to adapt the same technique for myriad treatments of injuries and diseases can open researchers’ minds about new paths for innovation.
Currently, there are 318 grants and 22 technology transfer opportunities in the area of nerve regeneration. Scientists and researchers can explore and compare the progress being made in their field to identify the work that is ongoing, as well as the white spaces where further research is needed.

Monitor Breakthroughs

As research accelerates in this area, ResoluteAI’s search alerts can be applied to any search query for which researchers would like to stay informed.
Screen Shot 2020-02-25 at 11.49.19 AMAdditionally, ResoluteAI’s Analytics view can show the organizations that are currently working with technology transfer opportunities, enabling researchers to connect across fields.

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Conducting seamless research on the treatments of neurodegenerative disease such as Alzheimer’s Disease allows clinicians to break out of their silos. Advances in clinical technologies, best practices, and new findings can inspire the research that can lead to even more adaptive treatments for different diseases. ResoluteAI creates search tools for science that empower researchers to make the connections that lead to the discovery of new treatment methods - and maybe one day, a cure to the diseases that plague a society.


ResoluteAI is the research platform for science. Foundation lets commercial science enterprises search aggregated scientific, regulatory, and business databases simultaneously. Nebula is our enterprise search tool for science. Combined with our interactive analytics and downloadable visualizations, ResoluteAI helps make connections that lead to breakthrough discoveries. Used in R&D, medical affairs, post market surveillance, and pharmacovigilance by scientific organizations around the world, ResoluteAI won the BCS Search Industry Award for Most Promising Start-Up in 2021.